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Advances in Pediatrics

Dental Caries: State of the Science for the Most Common Chronic Disease of Childhood

      Oral health is an integral part of overall health [
      • U.S. Department of Health and Human Services
      Oral health in America: a report of the surgeon general.
      ]. The oral health status of an individual reflects their general health status and, as such, is an important part of their well being. A body of knowledge is rapidly increasing on the association between oral and systemic health [
      • Bobetsis Y.A.
      • Barros S.P.
      • Offenbacher S.
      Exploring the relationship between periodontal disease and pregnancy complications.
      ,
      • Demmer R.T.
      • Desvarieux M.
      Periodontal infections and cardiovascular disease: the heart of the matter.
      ,
      • Mealey B.L.
      Periodontal disease and diabetes: a two-way street.
      ]. This should not be surprising considering that the mouth may serve as a portal of entry for disease, a source of contagion, a primary site for disease that can spread systemically, a frequent site of manifestations of systemic disease, and may contribute to increased morbidity caused by other systemic diseases.
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