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- The lifelong effects of early childhood adversity and toxic stress.Pediatrics. 2012; 129: e232-e246
- Adolescent brain development: a period of vulnerabilities and opportunities. Keynote address.Ann N Y Acad Sci. 2004; 1021: 1-22
- Sensitive periods in the development of the brain and behavior.J Cogn Neurosci. 2004; 16: 1412-1425
- The relationship of adverse childhood experiences to a history of premature death of family members.BMC Public Health. 2009; 9: 106
- Adverse childhood experiences and the risk of premature mortality.Am J Prev Med. 2009; 37: 389-396
- Effects of early life stress on cognitive and affective function: an integrated review of human literature.Psychopharmacology (Berl). 2011; 214: 55-70
- The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress.Dialogues Clin Neurosci. 2006; 8: 383-395
- Mechanisms linking early life stress to adult health outcomes.Proc Natl Acad Sci U S A. 2010; 107: 8507-8512
- Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The Adverse Childhood Experiences (ACE) Study.Am J Prev Med. 1998; 14: 245-258
- Childhood abuse, household dysfunction, and the risk of attempted suicide throughout the life span: findings from the Adverse Childhood Experiences Study.JAMA. 2001; 286: 3089-3096
- The science of early life toxic stress for pediatric practice and advocacy.Pediatrics. 2013; 131: 319-327
- Prenatal maternal stress and cord blood innate and adaptive cytokine responses in an inner-city cohort.Am J Respir Crit Care Med. 2010; 182: 25-33
- Do bullied children get ill, or do ill children get bullied? A prospective cohort study on the relationship between bullying and health-related symptoms.Pediatrics. 2006; 117: 1568-1574
- Toxic stress and brain development in young homeless children.in: Matto H.C. Strolin-Goltzman J. Ballan M. Neuroscience for social work: current research and practice. Springer, New York2013: 263-277
- Maternal stress beginning in infancy may sensitize children to later stress exposure: effects on cortisol and behavior.Biol Psychiatry. 2002; 52: 776-784
- Adverse childhood experiences: national and state-level prevalence.Child Trends, Bethesda (MD)2014 (Available at:)
- Perceived discrimination and health: a meta-analytic review.Psychol Bull. 2009; 135: 531-554
- Childhood adversity and adult chronic disease: an update from ten states and the District of Columbia, 2010.Am J Prev Med. 2015; 48: 345-349
Center for Youth Wellness in partnership with Public Health Institute. A hidden crisis: findings on adverse childhood experiences in California. 2014. Available at: http://www.centerforyouthwellness.org/resources. Accessed December 15, 2015.
- Adverse childhood experiences: assessing the impact on health and school engagement and the mitigating role of resilience.Health Affairs. 2014; 33: 2106-2115
- Adverse childhood experiences and dental health in children and adolescents.Community Dent Oral Epidemiol. 2015; 43: 193-199
- Association between adverse childhood experiences in the home and pediatric asthma.Ann Allergy Asthma Immunol. 2015; 114: 379-384
- The impact of adverse childhood experiences on an urban pediatric population.Child Abuse Negl. 2011; 35: 408-413
- Adverse childhood experiences and child health in early adolescence.JAMA Pediatr. 2013; 167: 622-629
Centers for Disease Control and Prevention. 2013 U.S. mortality multiple cause files. Available at: http://www.cdc.gov/nchs/data_access/Vitalstatsonline.htm. Accessed December 15, 2015.
- Early psychosocial exposures, hair cortisol levels, and disease risk.Pediatrics. 2015; 135: e1450-e1457
American Academy of Pediatrics. 2014. The medical home approach to identifying and responding to exposure to trauma. Available at: https://www.aap.org/en-us/Documents/ttb_medicalhomeapproach.pdf. Accessed December 15, 2015.
- Neuroscience, molecular biology, and the childhood roots of health disparities: building a new framework for health promotion and disease prevention.JAMA. 2009; 301: 2252-2259
- Biological sensitivity to context.Curr Dir Psychol Sci. 2008; 17: 183-187
- Stress and health: psychological, behavioral, and biological determinants.Annu Rev Clin Psychol. 2005; 1: 607-628
- Emotion circuits in the brain.Annu Rev Neurosci. 2000; 23: 155-184
- Physiology and neurobiology of stress and adaptation: central role of the brain.Physiol Rev. 2007; 87: 873-904
- Haggerty R.J. Sherrod L.R. Garmezy N. Stress, risk, and resilience in children and adolescents: processes, mechanisms, and interventions. Cambridge University Press, New York1996
- Cardiovascular response to stress.Physiol Rev. 1991; 71: 305-330
- The neuroendocrinology of stress: its relation to the hormonal milieu, growth and development.Growth Genet Horm. 1997; 13: 1-8
- Hypothalamic-pituitary-adrenal axis, neuroendocrine factors and stress.J Psychosom Res. 2002; 53: 865-871
- Neural regulation of endocrine and autonomic stress responses.Nat Rev Neurosci. 2009; 10: 397-409
- Child maltreatment and the developing HPA axis.Horm Behav. 2006; 50: 632-639
- Neuroendocrinology of stress.Endocrinol Metab Clin North Am. 2001; 30 (vii–viii): 695-728
- Endocrinology of the stress response.Annu Rev Physiol. 2005; 67: 259-284
- Changes in brain dopamine and acetylcholine release during and following stress are independent of the pituitary-adrenocortical axis.Brain Res. 1991; 538: 111-117
- Stress and the mesocorticolimbic dopamine systems.Ann N Y Acad Sci. 1988; 537: 138-147
- Amygdala: role in autonomic and neuroendocrine responses to stress.in: McCubbin J.A. Kaufman P.G. Nemeroff C.B. Stress, neuropeptides, and systemic disease. Academic Press, New York1991: 37
- Studies of the secretion of corticotropin-releasing factor and arginine vasopressin into the hypophysial-portal circulation of the conscious sheep. II. The central noradrenergic and neuropeptide Y pathways cause immediate and prolonged hypothalamic-pituitary-adrenal activation. Potential involvement in the pseudo-Cushing's syndrome of endogenous depression and anorexia nervosa.J Clin Invest. 1994; 93: 1439-1450
- Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue in rats.Am J Physiol. 1991; 260: R328-R334
- The neurobiology of stress: from serendipity to clinical relevance.Brain Res. 2000; 886: 172-189
- Allostasis: a new paradigm to explain arousal pathology.in: Fisher S. Reason J. Handbook of life stress, cognition and health. Wiley, New York1988: 629-649
- Adverse childhood experiences, allostasis, allostatic load, and age-related disease.Physiol Behav. 2012; 106: 29-39
- Protective and damaging effects of stress mediators.N Engl J Med. 1998; 338: 171-179
- The concept of allostasis in biology and biomedicine.Horm Behav. 2003; 43: 2-15
- Protective and damaging effects of stress mediators: central role of the brain.Dialogues Clin Neurosci. 2006; 8: 367-381
- Stress- and allostasis-induced brain plasticity.Annu Rev Med. 2010; 62: 431-445
- The prefrontal cortex as a key target of the maladaptive response to stress.J Neurosci. 2007; 27: 2781-2787
- If it goes up, must it come down? Chronic stress and the hypothalamic-pituitary-adrenocortical axis in humans.Psychol Bull. 2007; 133: 25-45
- The link between childhood trauma and depression: insights from HPA axis studies in humans.Psychoneuroendocrinology. 2008; 33: 693-710
- When not enough is too much: the role of insufficient glucocorticoid signaling in the pathophysiology of stress-related disorders.Am J Psychiatry. 2003; 160: 1554-1565
- Conceptual development of the immune system as a sixth sense.Brain Behav Immun. 2007; 21: 23-33
- Immunology and developmental psychopathology.in: Cicchetti D. Cohen D.J. Developmental psychopathology. 2nd edition. Wiley, New York2006: 677-709
- A mechanism converting psychosocial stress into mononuclear cell activation.Proc Natl Acad Sci U S A. 2003; 100: 1920-1925
- Chronic stress and age-related increases in the proinflammatory cytokine IL-6.Proc Natl Acad Sci U S A. 2003; 100: 9090-9095
- From inflammation to sickness and depression: when the immune system subjugates the brain.Nat Rev Neurosci. 2008; 9: 46-56
- Antiinflammatory action of glucocorticoids–new mechanisms for old drugs.N Engl J Med. 2005; 353: 1711-1723
- Neuroendocrine regulation of immunity.Annu Rev Immunol. 2002; 20: 125-163
- Neural aspects of immunomodulation: focus on the vagus nerve.Brain Behav Immun. 2010; 24: 1223-1228
- The relationship between cortisol, C-reactive protein and hypertension in African and Caucasian women: the POWIRS study.Cardiovasc J Afr. 2012; 23: 78-84
- The inflammatory reflex.Nature. 2002; 420: 853-859
- Psychological stress and susceptibility to the common cold.N Engl J Med. 1991; 325: 606-612
- Stress-induced immunomodulation: implications for infectious diseases?.JAMA. 1999; 281: 2268-2270
- The neuroendocrinology of stress and aging: the glucocorticoid cascade hypothesis.Endocr Rev. 1986; 7: 284-301
- Immune system dysregulation in adolescent major depressive disorder.J Affect Disord. 2009; 115: 177-182
- Relations between mucosal immunity and children's mental health: the role of child sex.Physiol Behav. 2010; 101: 705-712
- Antagonistic characteristics are positively associated with inflammatory markers independently of trait negative emotionality.Brain Behav Immun. 2008; 22: 753-761
- Cytokine genes TNF, IL1A, IL1B, IL6, IL1RN and IL10, and childhood-onset mood disorders.Neuropsychobiology. 2008; 58: 71-80
- Cytokines sing the blues: inflammation and the pathogenesis of depression.Trends Immunol. 2006; 27: 24-31
- The neurobiology of stress and development.Annu Rev Psychol. 2007; 58: 145-173
- Early care experiences and HPA axis regulation in children: a mechanism for later trauma vulnerability.Prog Brain Res. 2008; 167: 137-149
- Early life stress, the development of aggression and neuroendocrine and neurobiological correlates: what can we learn from animal models?.Front Neuroendocrinol. 2009; 30: 497-518
- Serotonergic blunting to meta-chlorophenylpiperazine (m-CPP) highly correlates with sustained childhood abuse in impulsive and autoaggressive female borderline patients.Biol Psychiatry. 2000; 47: 548-556
- Hypothalamic arousal, insulin resistance and type 2 diabetes mellitus.Diabet Med. 1999; 16: 373-383
- Cortisol, testosterone, and coronary heart disease: prospective evidence from the Caerphilly study.Circulation. 2005; 112: 332-340
- High anticipatory stress plasma cortisol levels and sensitivity to glucocorticoids predict severity of coronary artery disease in subjects undergoing coronary angiography.Metabolism. 2007; 56: 222-226
- Complementary and incremental mortality risk prediction by cortisol and aldosterone in chronic heart failure.Circulation. 2007; 115: 1754-1761
- Association of coronary artery disease with glucocorticoid receptor N363S variant.Hypertension. 2003; 41: 404-407
- The concepts of stress and stress system disorders. Overview of physical and behavioral homeostasis.JAMA. 1992; 267: 1244-1252
- Prenatal exposures to persistent and non-persistent organic compounds and effects on immune system development.Basic Clin Pharmacol Toxicol. 2008; 102: 146-154
- Hygiene hypothesis and prevalence of glomerulonephritis.Kidney Int Suppl. 2005; : S62-S67
- Socioeconomic status, stress, and immune markers in adolescents with asthma.Psychosom Med. 2003; 65: 984-992
- Stress and inflammation in exacerbations of asthma.Brain Behav Immun. 2007; 21: 993-999
- Social and environmental stressors in the home and childhood asthma.J Epidemiol Community Health. 2010; 64: 636-642
- Maternal intimate partner violence and increased asthma incidence in children: buffering effects of supportive caregiving.Arch Pediatr Adolesc Med. 2009; 163: 244-250
- Stress hormones, Th1/Th2 patterns, pro/anti-inflammatory cytokines and susceptibility to disease.Trends Endocrinol Metab. 1999; 10: 359-368
- The role of indoor allergens in the development of asthma.Curr Opin Allergy Clin Immunol. 2009; 9: 128-135
- The Seattle-King County healthy homes project: implementation of a comprehensive approach to improving indoor environmental quality for low-income children with asthma.Environ Health Perspect. 2002; 110: 311-322
- Epigenetics: what is it and why is it important to mental disease?.Br Med Bull. 2008; 85: 35-45
- Randy L. Jirtle, PhD: epigenetics a window on gene dysregulation, disease. Interview by Bridget M. Kuehn.JAMA. 2008; 299: 1249-1250
- Epigenetic control of fetal gene expression.BJOG. 2008; 115: 158-168
- The ageing epigenome: damaged beyond repair?.Ageing Res Rev. 2009; 8: 189-198
- Early life, the epigenome and human health.Acta Paediatr. 2009; 98: 1082-1084
- The early life environment and the epigenome.Biochim Biophys Acta. 2009; 1790: 878-885
- Imprinting evolution and human health.Mamm Genome. 2009; 20: 563-572
- Epigenetic programming by maternal behavior.Nat Neurosci. 2004; 7: 847-854
- Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse.Nat Neurosci. 2009; 12: 342-348
- Epigenetic mechanisms of perinatal programming of hypothalamic-pituitary-adrenal function and health.Trends Mol Med. 2007; 13: 269-277
- Epigenetic mechanisms mediating the long-term effects of maternal care on development.Neurosci Biobehav Rev. 2009; 33: 593-600
- Maternal care associated with methylation of the estrogen receptor-alpha1b promoter and estrogen receptor-alpha expression in the medial preoptic area of female offspring.Endocrinology. 2006; 147: 2909-2915
- Does the social environment contribute to asthma?.Immunol Allergy Clin North Am. 2008; 28 (x): 649-664
- Maternal presence serves as a switch between learning fear and attraction in infancy.Nat Neurosci. 2006; 9: 1004-1006
- A novel mouse model for acute and long-lasting consequences of early life stress.Endocrinology. 2008; 149: 4892-4900
- Developmental emergence of fear learning corresponds with changes in amygdala synaptic plasticity.Brain Res. 2008; 1200: 58-65
- Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene.Arch Gen Psychiatry. 2008; 65: 190-200
- Trauma exposure and stress-related disorders in inner city primary care patients.Gen Hosp Psychiatry. 2009; 31: 505-514
- Childhood life events and childhood trauma in adult patients with depressive, anxiety and comorbid disorders vs. controls.Acta Psychiatr Scand. 2010; 122: 66-74
- Childhood abuse is associated with increased startle reactivity in adulthood.Depress Anxiety. 2009; 26: 1018-1026
- Diabetes–role of epigenetics, genetics, and physiological factors.Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2009; 34: 837-845
- Children's memory for a mild stressor: the role of sympathetic activation and parasympathetic withdrawal.Dev Psychobiol. 2006; 48: 686-702
- Developmental origins of health and disease: environmental exposures.Semin Reprod Med. 2009; 27: 391-402
- Cancer susceptibility: epigenetic manifestation of environmental exposures.Cancer J. 2007; 13: 9-16
- Epigenetic regulation of gene expression in the inflammatory response and relevance to common diseases.J Periodontol. 2008; 79: 1514-1519
- Social enrichment during postnatal development induces transgenerational effects on emotional and reproductive behavior in mice.Front Behav Neurosci. 2009; 3: 25
- Epigenetics, DNA methylation, and chromatin modifying drugs.Annu Rev Pharmacol Toxicol. 2009; 49: 243-263
- The timing and quality of early experiences combine to shape brain architecture. Working paper #5.Center on the Developing Child at Harvard University, Cambridge (MA)2007 (Available at)
- Early rearing conditions alter immune responses in the developing infant primate.Pediatrics. 1992; 90: 505-509
- Early childhood stress is associated with elevated antibody levels to herpes simplex virus type 1.Proc Natl Acad Sci U S A. 2009; 106: 2963-2967
- Early childhood adversity, toxic stress, and the role of the pediatrician: translating developmental science into lifelong health.Pediatrics. 2012; 129: e224-e231
- Adverse childhood experiences and prescribed psychotropic medications in adults.Am J Prev Med. 2007; 32: 389-394
- Adverse childhood experiences and chronic obstructive pulmonary disease in adults.Am J Prev Med. 2008; 34: 396-403
- The impact of adverse childhood experiences on health problems: evidence from four birth cohorts dating back to 1900.Prev Med. 2003; 37: 268-277
- Adolescent violence perpetration: associations with multiple types of adverse childhood experiences.Pediatrics. 2010; 125: e778-e786
- The association between adverse childhood experiences and adolescent pregnancy, long-term psychosocial consequences, and fetal death.Pediatrics. 2004; 113: 320-327
- Adverse childhood experiences and sexually transmitted diseases in men and women: a retrospective study.Pediatrics. 2000; 106: E11
- Health consequences of adverse childhood experiences: a systematic review.J Am Assoc Nurse Pract. 2015; 27: 457-465