Children and adolescents with gender dysphoria are presenting for medical attention
at increasing rates.
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References
- Standards of care for the health of transsexual, transgender, and gender-nonconforming people, version 7.Int J Transgend. 2012; 13: 165-232
- Endocrine treatment of transsexual persons: an Endocrine Society clinical practice guideline.J Clin Endocrinol Metab. 2009; 94: 3132-3154
- Transgender representation in offline and online media: LGBTQ youth perspectives.J Hum Behav Soc Environ. 2015; 25: 606-617
- Transgender today.Monitor on Psychology. 2013; 44: 36
- Children and adolescents with gender identity disorder referred to a pediatric medical center.Pediatrics. 2012; 129: 418-425
- Approach to the patient: transgender youth: endocrine considerations.J Clin Endocrinol Metab. 2014; 99: 4379-4389
- Child and Adolescent Gender Center: a multidisciplinary collaboration to improve the lives of gender nonconforming children and teens.Pediatr Rev. 2012; 33: 273-275
- Clinical management of gender dysphoria in children and adolescents: the Dutch approach.J Homosex. 2012; 59: 301-320
- Is gender identity disorder in adolescents coming out of the closet?.J Sex Marital Ther. 2008; 34: 287-290
- Lesbian, gay, bisexual, and transgender-related content in undergraduate medical education.JAMA. 2011; 306: 971-977
- Institute of Medicine. The health of lesbian, gay, bisexual, and transgender people: building a foundation for better understanding. The National Academies Press, Washington, DC2011
- Current management of gender identity disorder in childhood and adolescence: guidelines, barriers and areas of controversy.Curr Opin Endocrinol Diabetes Obes. 2013; 20: 69-73
- Diagnostic and statistical manual of mental disorders.4th edition. American Psychiatric Publishing, Arlington (VA)2000
- Diagnostic and statistical manual of mental disorders.5th edition. American Psychiatric Publishing, Arlington (VA)2013
- An epidemiological and demographic study of transsexuals in The Netherlands.Arch Sex Behav. 1996; 25: 589-600
- Transgender health in Massachusetts: results from a household probability sample of adults.Am J Public Health. 2012; 102: 118-122
- Note on the effects produced on man by subcutaneous injections of a liquid obtained from the testicles of animals.Lancet. 1889; 134: 105-107
- On crystalline male hormone from testicles (testosterone) effective as from urine or from cholesterol.Hoppe Seylers Z Physiol Chem. 1935; 233: 281
- Sexualhormone VII. Über die künstliche Herstellung des Testikelhormons Testosteron (Androsten-3-on-17-ol).Helv Chim Acta. 1935; 18: 1264-1275
- The preparation of the crystalline follicular ovarian hormone: Theelin.J Biol Chem. 1930; 87: 357-371
- Über 'Progynon' ein krystallisiertes weibliches Sexualhormon.Naturwissenschaften. 1929; 17: 879
- The chemistry of oestrin.Biochem J. 1930; 24: 435-445
- Reindarstellung der Hormone aus dem Corpus luteum (II. Mitteil.).Ber Dtsch Chem Ges. 1934; 67: 1624-1626
- Crystalline progestin.J Biol Chem. 1934; 107: 321-336
- Sex hormone series.Ber Dtsch Chem Ges. 1938; 71: 1024-1032
- Neue per os-wirksame weibliche Keimdrüsenhormon-Derivate: 17-Aethinyl-oestradiol und Pregnen-in-on-3-ol-17.Naturwissenschaften. 1938; 26: 96
- Long-term treatment of transsexuals with cross-sex hormones: extensive personal experience.J Clin Endocrinol Metab. 2008; 93: 19-25
- Sexualpathologie: T. Sexuelle Zwischenstufen; Das Männliche Weib Und der Weibliche Mann. vol. 2. A. Marcus & E. Webers, Bonn (Germany)1918
- Man into woman: an authentic record of a change of sex.Jarrold Publishers, Norwich (England)1933
- Development of feminizing genitoplasty for gender dysphoria.J Sex Med. 2007; 4: 981-989
Christine J. Available at: www.christinejorgensen.org. Accessed December 16, 2015.
Dec. 1, 1952: Ex-GI becomes blonde beauty. Wired. 2010. Available at: www.wired.com/2010/12/1201first-sex-change-surgery, Accessed December 16, 2015.
- Ein Transvestit.Z Kriminalistische Wissen. 1949; 3: 91-92
- Transvestism: hormonal, psychiatric, and surgical treatment.JAMA. 1953; 152: 391-396
- The transsexual phenomenon: a scientific report on transsexualism and sex conversion in the human male and female.The Julian Press, Inc. Publishers, New York1966
- As nature made him: the boy who was raised as a girl.2nd edition. Harper Perennial, New York2006
- Long-Term treatment of central precocious puberty with a long-acting analogue of luteinizing hormone-releasing hormone.N Engl J Med. 1983; 309: 1286-1290
- Pubertal delay as an aid in diagnosis and treatment of a transsexual adolescent.Eur Child Adolesc Psychiatry. 1998; 7: 246-248
- Non invasive fetal sex determination using cell-free DNA: a systematic review and meta-analysis.JAMA. 2011; 306: 627-636
- A cognitive-developmental analysis of children’s sex role concepts and attitudes.in: Maccoby E. The development of sex differences. Stanford University, Stanford (CA)1966: 82-173
- The dynamic development of gender variability.J Homosex. 2012; 59: 398-421
- Fetal hormones and the brain: effect on sexual dimorphism of behavior - a review.Arch Sex Behav. 1971; 1: 241-262
- Sex/gender: biology in a social world.Routledge, New York2012
- Normal sexual dimorphism of the adult human brain assessed by in vivo magnetic resonance imaging.Cereb Cortex. 2001; 11: 490-497
- A sex difference in the human brain and its relation to transsexuality.Nature. 1995; 378: 68-70
- Gender identity disorder in twins: a review of the case report literature.J Sex Med. 2012; 9: 751-757
- Sexual differentiation of human behavior: effects of prenatal and pubertal organizational hormones.Front neuroendocrinology. 2011; 32: 183-200
- Hormones, context, and “brain gender”: a review of evidence from congenital adrenal hyperplasia.Soc Sci Med. 2012; 74: 1738-1744
- Gender dysphoria and gender change in chromosomal females with congenital adrenal hyperplasia.Arch Sex Behav. 2005; 34: 389-397
- Discordant sexual identity in some genetic males with cloacal exstrophy assigned to female sex at birth.N Engl J Med. 2004; 350: 333-341
- Cognitive theories of early gender development.Psychol Bull. 2002; 128: 903-933
- Increased gender variance in autism spectrum disorders and attention deficit hyperactivity disorder.Arch Sex Behav. 2014; 43: 1525-1533
- Gender Identity disorder: a literature review from a developmental perspective.Isr J Psychiatry Relat Sci. 2010; 47: 132-138
- Clinical practice. Care of transsexual persons.N Engl J Med. 2011; 364: 1251-1257
- A follow-up study of girls with gender identity disorder.Dev Psychol. 2008; 44: 34-45
- Psychosexual outcome of gender dysphoric children.J Pers Assess. 2009; 91: 545-552
- Clinical management of gender identity disorder in adolescents: a protocol on psychological and paediatric endocrinology aspects.Eur J Endocrinol. 2006; 155: S131-S137
- Desisting and persisting gender dysphoria after childhood: a qualitative follow-up study.Clin Child Psychol Psychiatry. 2011; 16: 499-516
- Factors associated with desistence and persistence of childhood gender dysphoria: a quantitative follow-up study.J Am Acad Child Adolesc Psychiatry. 2013; 52: 582-590
- Experiences of transgender-related discrimination and implications for health: results from the Virginia Transgender Health Initiative Study.Am J Public Health. 2013; 103: 1820-1829
- National transgender discrimination survey report on health and health care.National Center for Transgender Equality; National Gay and Lesbian Task Force, Washington, DC2010
- Transgender youth and life-threatening behaviors.Suicide Life Threat Behav. 2007; 37: 527-537
- Psychiatric impact of gender-related abuse across the life course of male-to-female transgender persons.J Sex Res. 2010; 47: 12-23
- Baseline physiologic and psychosocial characteristics of transgender youth seeking care for gender dysphoria.J Adolesc Health. 2015; 57: 374-380
- Transgender female youth and sex work: HIV risk and a comparison of life factors related to engagement in sex work.AIDS Behav. 2009; 13: 902-913
- Mental health of transgender youth in care at an adolescent urban community health center: a matched retrospective cohort study.J Adolesc Health. 2015; 56: 274-279
- The 2011 National School Climate Survey: the experiences of lesbian, gay, bisexual and transgender youth in our Nation’s schools.Gay, Lesbian & Straight Education Network, New York2012
- Autism spectrum disorders in gender dysphoric children and adolescents.J Autism Dev Disord. 2010; 40: 930-936
- A developmental, biopsychosocial model for the treatment of children with gender identity disorder.J Homosex. 2012; 59: 369-397
- An affirmative intervention for families with gender variant children: parental ratings of child mental health and gender.J Sex Marital Ther. 2010; 36: 6-23
- Guidelines for psychological practice with transgender and gender nonconforming people.Am Psychol. 2015; 70: 832-864
- Puberty suppression in adolescents with gender identity disorder: a prospective follow-up study.J Sex Med. 2011; 8: 2276-2283
- Young adult psychological outcome after puberty suppression and gender reassignment.Pediatrics. 2014; 134: 1-9
- Differentiation of external genital structures.in: Sperling M.A. Pediatric endocrinology. 3rd edition. Saunders Elsevier, Philadelphia2008: 132
- Activation of the hypothalamic-pituitary-gonadal axis in infancy: minipuberty.Horm Res Paediatr. 2014; 82: 73-80
- Puberty and the testis.in: Sperling M.A. Pediatric endocrinology. 3rd edition. Saunders Elsevier, Philadelphia2008: 676-679
- Development of the female reproductive system.in: Sperling M.A. Pediatric endocrinology. 3rd edition. Saunders Elsevier, Philadelphia2008: 532-559
- Adolescence.in: Kligman R.M. Behrman R.E. Jenson H.B. Nelson textbook of pediatrics. 18th edition. Saunders Elsevier, Philadelphia2007: 60-65
- Variations in pattern of pubertal changes in girls.Arch Dis Child. 1969; 44: 291-303
- Variations in the pattern of pubertal changes in boys.Arch Dis Child. 1970; 45: 13-23
- Growth and normal puberty.Pediatrics. 1998; 101: 507-511
- Serving transgender youth: challenges, dilemmas, and clinical examples.Prof Psychol Res Pr. 2015; 46: 37-45
- Use of a potent, long acting agonist of gonadotropin-releasing hormone in the treatment of precocious puberty.Endocr Rev. 1986; 7: 24-33
- The effect of medroxyprogesterone acetate on gonadotropin secretion in girls with precocious puberty.Am J Med Sci. 1975; 269: 375-381
- Effect of sex steroid use on cardiovascular risk in transsexual individuals: a systematic review and meta-analyses.Clin Endocrinol (Oxf). 2010; 72: 1-10
- Effects of sex steroids on components of the insulin resistance syndrome in transsexual subjects.Clin Endocrinol (Oxf). 2003; 58: 562-571
- Sex steroids, insulin, and arterial stiffness in women and men.Hypertension. 1999; 34: 590-597
- A long-term follow-up study of mortality in transsexuals receiving treatment with cross-sex hormones.Eur J Endocrinol. 2011; 164: 635-642
- Female-to-male transgender quality of life.Qual Life Res. 2006; 15: 1447-1457
- The social costs of gender nonconformity for transgender adults: implications for discrimination and health.Socio Forum. 2005; 30: 809-831
- A simple intervention raised resident-physician willingness to assist transgender patients seeking hormone therapy.Endocr Pract. 2015; 21: 1134-1142
- Implementing curricular and institutional climate changes to improve health care for individuals who are LGBT, gender nonconforming, or born with DSD.Association of American Medical Colleges, Washington, DC2014
- Resource list: clinical care programs for gender-nonconforming children and adolescents.Pediatr Ann. 2014; 43: 238-244
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Published online: June 03, 2016
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